Left Ventricular Non-Compaction Cardiomyopathy

First described 80 years or so ago, it occurs secondary to the failure of left ventricle (or sometimes RV) compaction during embryogenesis. 

As normal development progresses, the trabeculations become compacted transforming the heart muscle from sponge-like to smooth and solid.  When compaction does not occur, you develop noncompaction syndrome.

These trabeculations typically occur at the bottom of the heart but can be seen anywhere in the left ventricle. 

Individuals with LVNC may also have hypertrophic cardiomyopathy, dilated cardiomyopathy, or restrictive cardiomyopathy



- TM Smith, D.O. @RosenelliEM



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