Causes of Unintentional Weight Loss - Differential Diagnosis

Malignancy 

 - Tumor effect* (esp. Gl, lung, lymphoma)

 - Treatment effect*: Chemotherapy, Chronic radiation enteritis

Non-Malignant Gl Illness: IBD, Chronic mesenteric ischemia, Malabsorption (Celiac disease, Chronic pancreatitis)

Psychiatric: Depression, Eating disorders

Infections: HIV/AIDS, Tuberculosis

Endocrine: Uncontrolled diabetes, Hyperthyroidism, Chronic adrenal insufficiency

Neuro: Dementia, Stroke, Parkinson's Disease

Other: Food insecurity

Chronic illness: Heart failure ("cardiac cachexia"), COPD ("pulmonary cachexia")

Medications: Cholinesterase inhibitors, SGLT2 inhibitors, GLP-I agonists

Drugs: Alcohol, Stimulants



- Dr. Eric Strong @DrEricStrong - Strong Medicine https://www.youtube.com/c/EricsMedicalLectures/



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