Causes of Purpura - Differential Diagnosis

Disruption in Vascular Integrity: 

 • Trauma, Infection, Vasculitis, Drug induced vasculitis, Inherited collagen vascular disorders, Nutritional deficiencies (Vitamin C), Pigmented purpuric dermatoses

Abnormality in 1°/2° Hemostasis:

 • Primary hemostasis: Thrombocytopenia, Platelet dysfunction

 • Clotting factor deficiency



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