Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign")



Asboe-Hansen sign is the extension of an unruptured blister with the application of pressure. Best-detected by drawing a margin around the bulla prior.



Asboe-Hansen sign is a useful clinical tool for diagnosing toxic epidermal necrolysis (TEN).



Asboe-Hansen sign can be employed to generate a fresh bulla for lesional skin biopsy in the evaluation of TEN.



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