Dilaudid vs Morphine Side Effects Review

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Potential differences:

Pruritus: While most studies show similar rates of pruritus, two studies reported a lower incidence of pruritus with hydromorphone.
Cognitive Function and Mood: One study found that patients receiving hydromorphone had poorer cognitive performance but better mood compared to those receiving morphine.
Renal Failure: Due to a difference in how the drugs are metabolized, hydromorphone might be better tolerated than morphine in patients with renal failure, although this needs further study.