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Tapentadol is a prescription medication used primarily for managing moderate to severe pain, particularly when other pain relief methods are not sufficient. It belongs to a class of drugs known as opioid analgesics, which work by altering the way the brain and nervous system respond to pain. Tapentadol is prescribed for the relief of pain that is severe enough to require daily, around-the-clock treatment when other pain treatments, such as non-opioid pain medicines or immediate-release opioid medicines, do not treat your pain well enough or you cannot tolerate them. It is often used in cases where chronic pain is present, such as due to injuries, surgery, or conditions like osteoarthritis.